On 7 February 2021, the Minister of Health of the Democratic Republic of the Congo declared an outbreak of Ebola Virus Disease (EVD) after the laboratory confirmation of one case in Butembo, North Kivu Province. The case was a 42-year-old female living in Masoya Health Area, Biena Health Zone. She was a spouse of an EVD survivor, who has been followed up and whose biological samples have tested negative since 28 September 2020.
On 25 January 2021, the case presented with nasal bleeding. From 25 January to 1 February, she reportedly received outpatient care in Ngubi health center. From 1 to 3 February, she was admitted to Masoya health center with signs of physical weakness, dizziness, joint pain, epigastric pain, liquid stools, headache and difficulty breathing. On 3 February, a blood sample was collected for EVD testing due to her epidemiological link with an EVD survivor. On the same day, she was referred to Matanda Hospital, in Katwa Health Zone, Butembo territory following the deterioration of her condition. She was admitted to the intensive care unit the same day and died on 4 February. On 5 February, the body was buried in Musienene Health Zone, not under safe burial practices.